US6599251B2 - Continuous Non-invasive Blood Pressure Monitoring Method And Apparatus - Google Patents

This invention relates to blood stress monitoring gadgets of the type which measure transit occasions of pulses in a topic's blood circulatory system and BloodVitals tracker compute an estimated blood pressure from the measured pulse transit times. One approach is to insert a strain sensor directly into a suitable artery in the topic. This approach gives accurate and instantaneous blood pressure measurements. A surgical process is required to introduce the strain sensor. The fistula by means of which the lead exits the subject's body can provide a pathway for infection. Such devices are extensively utilized in hospitals and medical doctors' places of work for making routine blood strain measurements however usually are not well adapted to offering steady blood stress monitoring. Oscillometric blood stress measurements are made through the use of a transducer to detect and measure stress waves in a strain cuff as blood surges by an artery constricted by the stress cuff. Many at the moment available digital blood strain monitors use the oscillometric methodology for determining blood stress.

30 seconds. Further, the cuff compresses underlying tissues. Over an extended time period this can cause tissue harm. Another problem with prior art PTT blood strain measurements is that the relationship between blood stress and the time taken for pulses to transmit a portion of the blood circulatory system is totally different for each subject. Thus, Blood Vitals it is essential to calibrate a PTT blood strain measurement system for every topic. ARTRACTM 7000 which used two photometric sensors, one on the ear and one other on a finger, BloodVitals tracker to measure diastolic blood strain. This machine apparently used the distinction in arrived occasions of pulses at the ear and finger to measure the pulse transit time. This system apparently computed systolic pressure from the pulse quantity. This relationship, which is understood because the Moens-Korteweg-Hughes equation is described in more element under. Moens-Korteweg-Hughes equation is determined by the elasticity and BloodVitals tracker geometry of blood vessels and is extremely nonlinear. This invention supplies blood strain measurement strategies and apparatus which keep away from a number of the disadvantages of the prior art.

Preferred embodiments of the invention are suitable for BloodVitals tracker steady non-invasive blood stress ("CNIBP") monitoring. One side of the invention provides methods for monitoring blood strain. P zero , measuring the elapsed time T zero corresponding to the reference blood stress and determining values for each of the constants a and b from P zero and BloodVitals health T 0 . P 0 and a corresponding time difference T zero between the primary and second pulse alerts; from the reference blood pressure and corresponding time difference, determining a first plurality of constant parameters in a multi-parameter equation relating blood stress and the time-distinction; monitoring the topic's blood pressure by periodically measuring a time distinction T between the first and BloodVitals tracker second pulse indicators; computing an estimated blood strain, P, from the time difference, T, using the multi-parameter equation and the first plurality of constant parameters. 3 and c four are predetermined constants. T comprises measuring a primary time distinction T S for higher portions (ie portions corresponding typically to the elements of the indicators associated with systolic blood pressure) of the primary and second signals.

Measuring the primary time distinction might comprise maximizing a cross-correlation between the first and second pulse indicators. Another side of the invention provides a method for estimating a blood pressure of a topic. Yet one more aspect of the invention gives a technique for estimating the blood pressure, P, of a topic. P, of a subject. One more aspect of the invention supplies a way for estimating the blood pressure, P, of a subject. P 0 and measuring a corresponding time difference, T zero , between corresponding factors of the first and second pulse signals; from the reference blood stress and BloodVitals home monitor corresponding time distinction, determining a plurality of fixed parameters in a multi-parameter equation relating blood strain and the time difference by: figuring out a first parameter of the plurality of parameters as a predetermined operate of the corresponding time difference; and, figuring out a second parameter of the plurality of parameters as a predetermined operate of the reference blood stress and the time distinction; and, subsequently monitoring the topic's blood pressure by figuring out a time difference, T, between corresponding points of the first and second pulse alerts and computing an estimated blood pressure from the time difference T using the multi-parameter equation and the first and second parameters.